Michael holds a faculty appointment as an Associate Professor, in the Department of Biochemistry, University of Cape Coast, Ghana. He seeks to translate his understanding of basic cell and molecular mechanisms involved in disease conditions into novel therapeutic approaches. Michael employs biochemical, microbial, molecular, pharmacological, and molecular computational chemistry techniques/tools to investigate and understand pathophysiological conditions and receptor-ligand interactions, and in the process identify drug targets and discover new therapeutic agents. A major research effort is the development of a novel technique for culturing Helicobacter pylori which was published in the Journal of Tropical Medicine in 2018. The use of this technique led to the first successful isolation of Helicobacter pylori in Ghana. This milestone has paved a way for studies regarding the drug resistance profile of Helicobacter pylori in Ghana and this could translate into good healthcare service for peptic ulcer patients. 

Michael is a member of many prestigious professional groups such as the Western Africa Network of Natural Products Research Scientists (WANNPRES), American Society for Microbiology (ASM), and currently the President of the Ghana Science Association, Cape Coast branch. He is also a lead collaborator for Ghana in an NIH project working on Helicobacter pylori genome and a collaborator with WACCBIP, University of Ghana, Legon. Michael is a peer reviewer for a number of International Journals hosted by Elsevier, Hindawi, Bentham Science, Informa Publishing Company, Springer Science, Institute of Molecular Physiology and Genetics, Croatian Society of Medical Biochemistry and Laboratory Medicine. He serves as an External Assessor of academic programs / Theses for Kwame Nkrumah University of Science and Technology, University of Ghana, and an Internal Assessor for the University of Cape Coast. Michael has served as a member/chairman of many committees involving strategic planning, policy, project management, and accreditation of university education programs for the National Accreditation Board now Ghana Tertiary Education Commission (GTEC). Michael is currently the Head, Department of Biochemistry and also the Vice-Dean, School of Biological Sciences.