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About

Profile of Dr. Isaac Tabiri Henneh (PhD, MPhil, BPharm, MPSGh)


Isaac Tabiri Henneh is a Lecturer at the Department of Pharmacotherapeutics and Pharmacy Practice and the Coordinator for the Department of Pharmaceutical Microbiology, School of Pharmacy and Pharmaceutical Sciences, University of Cape Coast. Ghana. He holds a Bachelor’s degree in Pharmacy and an MPhil degree in Pharmacology, KNUST, Ghana as well as a PhD in Drug Discovery and Toxicology from the University Cape Coast, UCC, Ghana.

His research focuses on validation of crude extracts, isolation of bioactive compounds from medicinal plants and repurposing of approved orthodox drugs for the management of pain and inflammatory disorders, CNS disorders and parasitic infections. He has worked on bioactive compounds such as β-amyrin, polpunonic acid, xylopic acid, cryptolepine, erythroivorensin, and bergapten. He has so far published thirty peer reviewed articles in high impact journals and presented aspects of his research at several local and international conferences. He is an alumnus of the International Brain Research Organization (IBRO) schools as well as the Society for Medicinal Plant and Natural Product Research (GA-Germany) Young Researcher Workshop.

He is a recipient of several awards and grants. These include the Most Outstanding Researcher Award in the College of Health and Allied Sciences and the Dean’s Excellence Award at the 53rd (2020) Congregation of the University of Cape Coast, Ghana. He has also won four Best Presenter Awards at international scientific conferences. He was also awarded the Overall Best Student of the 2005 graduating class of SDA Secondary School, Bekwai-Ashanti. Additionally, he has won seven Research Support Grants from the Directorate of Research, Innovation and Consultancy (DRIC-UCC) as principal investigator and co-investigator. He is a reviewer for the Journal of Ethnopharmacology, PLOS ONE, Scientific African (Elsevier), Evidence-based Complementary and Alternate Medicine and several other reputable journals. He is the founder and CEO of the Sustainable Recovery and Empowerment (SURE) Centre: a registered not for profit Non-governmental Organization (NGO) in Ghana that promotes responsible drug use. Through his NGO, he has received funding from the US Embassy-Accra via the BrightHill Empowerment Initiative to undertake a project dubbed Recovering Addicts Programmme (RECAP).

Focus & expertise

Academic interests · number = colleagues who share it

Background

🎓 Education & qualifications

Doctor of Philosophy in Drug Discovery and Toxicology

University of Cape Coast

2019

Master of Philosophy in Pharmacology

Kwame Nkrumah University of Science and Technology

2017

Career & positions

Coordinator

Department of Pharmaceutical Microbiology

Jun, 2022 to Feb, 2023

Head of Department

Department of Pharmaceutical Microbiology

Aug, 2023 to Aug, 2025

Vice-Dean

School of Pharmacy and Pharmaceutical Science

Aug, 2025 to Aug, 2025

Publications 57 works

ORCID 0000-0002-6830-0283 →

2026

Anxiolytic and Anticonvulsant Effects of Ziziphus abyssinica Extract and β-Amyrin with Associated Neuroprotection: Behavioral, Biochemical, and Computational Evidence

Isaac Tabiri Henneh, Fabao Zhao, Robert Peter Biney, Francis Ackah Armah et al.

SSRN Electronic Journal · Preprint · Source: OpenAlex + ORCID

Assessment of the Safety Profile of Purified Pentadesma butyracea (Clusiaceae) Gum Intended as a Pharmaceutical Excipient

Mary-Ann Archer, Kwabena Ofori-Kwakye, Raphael Johnson, Ernest Amponsah Asiamah et al.

Journal of Toxicology · Article · Source: OpenAlex + ORCID

Comprehensive sub-chronic toxicological profiling of illegal artisanal small-scale mining-polluted river bodies in four regions of Ghana

Du-Bois Asante, George Yaw Hadzi, Samuel E. Naaman, Michael Woode et al.

Toxicology Reports · Article · Source: OpenAlex

Health System Determinants of Medication Error Underreporting in Ghana: A Nationwide Cross-Sectional Study

Stephen Mensah Arhin, Anthony Kwao Fosu, Joseph Arhin, Isaac Tabiri Henneh et al.

Research Square · Preprint · Source: OpenAlex

Medication error reporting in Ghana: A multicenter assessment of healthcare professionals’ knowledge, attitudes and practices

Stephen Mensah Arhin, Isaac Tabiri Henneh, Kwasi Sobre Nkrumah, Ewura Seidu Yahaya et al.

PLoS ONE · Article · Source: OpenAlex

Medication errors and medication error reporting practices in Ghana: a systematic review

Stephen Mensah Arhin, Isaac Tabiri Henneh, Theodora Dedo Azu, Joseph Arhin et al.

Therapeutic Advances in Drug Safety · Review · Source: OpenAlex + ORCID

Pain Experience and Patient‐Reported Barriers to Analgesic Use in Emergency Care in Ghana: A Cross‐Sectional Study

Stephen Mensah Arhin, Isaac Tabiri Henneh, Joseph Roger Arhin, James Kojo Prah et al.

Health Science Reports · Article · Source: OpenAlex + ORCID

2025

The prevalence, pattern of use and impact of traditional, complementary and alternative medicine (TCAM) among patients with end stage renal disease undergoing haemodialysis at a tertiary health facility in Ghana

Joseph Acquah-Mills, Isaac Tabiri Henneh, Stephen Mensah Arhin, Martins Ekor

Clinical Traditional Medicine and Pharmacology · Article · 9 citations · Source: OpenAlex + ORCID

Coping strategies of Ghanaian couples after unsuccessful infertility treatment: An exploratory qualitative study

Stephen Mensah Arhin, Kwesi Boadu Mensah, Isaac Tabiri Henneh, Felix Yirdong et al.

PLoS ONE · Article · 3 citations · Source: OpenAlex

Assessment of the Water Quality and Toxicological Effects of Toxic Metals in Selected Water Bodies around Gold Mining Areas in Ghana

George Yaw Hadzi, Isaac Tabiri Henneh, Joseph Kwaku Adjei, Albert Ofori et al.

Research Square · Preprint · 1 citation · Source: OpenAlex

Exploring the antidepressant-like effect of stigmasterol using network pharmacology with molecular docking and in vivo experimental validation

Robert Peter Biney, Isaac Blessed Mensah, Akua Afriyie Karikari, Aaron Opoku Antwi et al.

Scientific Reports · Article · 1 citation · Source: OpenAlex

Bioprospecting the antidiabetic potential of aqueous seed extract of Allanblackia floribunda Oliv. (Clusiaceae)

John Alake, Wisdom Ahlidja, Isaac Tabiri Henneh, Augustine Kwabil et al.

Food Chemistry Advances · Article · Source: OpenAlex + ORCID

Exploring the antidepressant-like effects of stigmasterol using network pharmacology with molecular docking and in vivo experimental validation: Involvement of serotonin modulation

Robert Peter Biney, Isaac Blessed Mensah, Akua Afriyie Karikari, Aaron Opoku Antwi et al.

Research Square · Preprint · Source: OpenAlex

β-Amyrin's Antidepressant-Like Activity in Mice and Zebrafish: Mechanistic Pathways and In Silico Molecular Interactions (Abstract ID: 169408)

Isaac Tabiri Henneh, Fabao Zhao, Robert Peter Biney, Kofi Boateng et al.

Journal of Pharmacology and Experimental Therapeutics · Article · Source: OpenAlex

2024

Pharmacological and phytochemical properties of a promising African medicinal plant, Sterculia setigera Delile: A systematic review

Wisdom Ahlidja, Elvis Fiam Amegayibor, Lily Addae, Evans Kwabena Abor et al.

Scientific African · Review · 7 citations · Source: OpenAlex + ORCID

Acute Oral Toxicological Profile of Croton membranaceus Mull. Arg. Aqueous Stem Extract, a Herbal Treatment for Benign Prostate Hyperplasia, in Male Sprague–Dawley Rats

Daniel Kwame Afriyie, Elvis Ofori Ameyaw, Isaac Tabiri Henneh, George Awuku Asare et al.

Journal of Toxicology · Article · 6 citations · Source: OpenAlex + ORCID

Antinociceptive and anti-ulcerogenic effect of hydroethanolic stem bark extract of Ricinodendron heudelotii (Baill.) Pierre ex. Heckel (Euphorbiaceae): Involvement of the opioidergic pathway and attenuation of oxidative stress

Isaac Tabiri Henneh, Wisdom Ahlidja, Ernest Amponsah Asiamah, Denzel Opoku-Kwabi et al.

Journal of Traditional and Complementary Medicine · Article · 1 citation · Source: OpenAlex + ORCID

In silico, in vitro and in vivo antiplasmodial activity of β-amyrin and its potential synergistic effect when co-administered with artesunate

Isaac Tabiri Henneh, Isaac Yaw Attah, Silas Acheampong Osei, Ernest Obese et al.

Journal of Pharmacology and Experimental Therapeutics · Article · Source: OpenAlex

2023

Modulating Effects of the Hydroethanolic Leaf Extract of Persicaria lanigera R. Br. Soják (Polygonaceae) against Acute Inflammation

Meshack Antwi-Adjei, Ernest Obese, Emmanuel A. Adakudugu, Isaac Tabiri Henneh et al.

The Scientific World JOURNAL · Article · 3 citations · Source: OpenAlex + ORCID

ANTI-EPILEPTOGENIC ACTIVITY OF ZIZIPHUS ABYSSINICA ROOT BARK EXTRACT AND ITS ISOLATED BIOACTIVE COMPOUND, Β-AMYRIN

Isaac Tabiri Henneh, Robert Peter Biney, Silas Acheampong, Ernest Obese et al.

IBRO Neuroscience Reports · Article · 1 citation · Source: OpenAlex

Pharmacotherapy for Infertility in Ghana: A Prospective Study on Prescription Patterns and Treatment Outcomes among Women undergoing Fertility Treatment

Stephen Mensah Arhin, Kwesi Boadu Mensah, Evans Kofi Agbeno, Isaac Tabiri Henneh et al.

Current Therapeutic Research · Article · 1 citation · Source: OpenAlex

2022

Depression in Sub-Saharan Africa

Ismail Gbadamosi, Isaac Tabiri Henneh, Oritoke M. Aluko, Emmanuel Yawson et al.

IBRO Neuroscience Reports · Article · 111 citations · Source: OpenAlex

Pharmacotherapy of infertility in Ghana: Why do infertile patients discontinue their fertility treatment?

Stephen Mensah Arhin, Kwesi Boadu Mensah, Evans Kofi Agbeno, Diallo Abdoul Azize et al.

PLoS ONE · Article · 14 citations · Source: OpenAlex + ORCID

Acute toxicity profile and gastroprotective potential of ethanolic leaf extract of Manihot esculenta Crantz

Isaac Tabiri Henneh, Wisdom Ahlidja, John Alake, Hakeem Mohammed et al.

Scientific African · Article · 12 citations · Source: OpenAlex + ORCID

Ziziphus abyssinica root bark extract ameliorates paracetamol-induced liver toxicity in rats possibly via the attenuation of oxidative stress

Isaac Tabiri Henneh, Wisdom Ahlidja, John Alake, Augustine Kwabil et al.

Toxicology Reports · Article · 12 citations · Source: OpenAlex

2021

Protective Effect of Bergapten against Human Erythrocyte Hemolysis and Protein Denaturation In Vitro

Douglas B. Aidoo, Daniels Konja, Isaac Tabiri Henneh, Martins Ekor

International Journal of Inflammation · Article · 71 citations · Source: OpenAlex + ORCID

Allanblackia floribunda Seed Extract Attenuates the Ethanol‐Induced Gastric Ulcer in Rats via the Inhibition of TNF‐α and INF‐γ Levels and Modulation in the Expression of Ki67 Protein

Francis Ackah Armah, Isaac Tabiri Henneh, John Alake, Wisdom Ahlidja et al.

BioMed Research International · Article · 26 citations · Source: OpenAlex + ORCID

Antinociceptive effect of the hydroethanolic leaf extract of Calotropis procera (Ait) R. Br. (Apocynaceae): Possible involvement of glutamatergic, cytokines, opioidergic and adenosinergic pathways

Ernest Obese, Robert Peter Biney, Isaac Tabiri Henneh, Daniel Anokwah et al.

Journal of Ethnopharmacology · Article · 22 citations · Source: OpenAlex + ORCID

Analgesic Effect of Ziziphus abyssinica Involves Inhibition of Inflammatory Mediators and Modulation of KATP Channels, Opioidergic and Nitrergic Pathways

Isaac Tabiri Henneh, Francis Ackah Armah, Elvis Ofori Ameyaw, Robert Peter Biney et al.

Frontiers in Pharmacology · Article · 14 citations · Source: OpenAlex

The Anticonvulsant Effect of Hydroethanolic Leaf Extract of Calotropis procera (Ait) R. Br. (Apocynaceae)

Ernest Obese, Robert Peter Biney, Isaac Tabiri Henneh, Emmanuel A. Adakudugu et al.

Neural Plasticity · Article · 12 citations · Source: OpenAlex + ORCID

Antidepressant and Anxiolytic Effects and Subacute Toxicity of the Aerial Parts of Psychotria ankasensis J.B.Hall (Rubiaceae) in Murine Models

Francis Ackah Armah, Isaac Tabiri Henneh, Isaac Kingsley Amponsah, Robert Peter Biney et al.

Evidence-based Complementary and Alternative Medicine · Article · 7 citations · Source: OpenAlex + ORCID

A Hydroethanolic Leaf Extract of Persicaria lanigera Possesses Antinociceptive Activity through Cytokine and Glutamatergic Pathways In Vivo

Ernest Obese, Elvis Ofori Ameyaw, Robert Peter Biney, Isaac Tabiri Henneh et al.

Evidence-based Complementary and Alternative Medicine · Article · 5 citations · Source: OpenAlex + ORCID

Celecoxib exhibits therapeutic potential in experimental model of hyperlipidaemia

Martins Ekor, Phyllis Elsie Owusu Agyei, Ernest Obese, Robert Peter Biney et al.

PLoS ONE · Article · 4 citations · Source: OpenAlex

Celecoxib exhibits therapeutic potential in experimental model of hyperlipidaemia

Martins Ekor, Phyllis Elsie Owusu Agyei, Ernest Obese, Robert Peter Biney et al.

bioRxiv (Cold Spring Harbor Laboratory) · Preprint · 1 citation · Source: OpenAlex

Cercariacidal activity of ripe and unripe lime oil extracts on Schistosoma mansoni

Francis Ackah Armah, Isaac Tabiri Henneh, Christian K Adoko, Felix Acheampong et al.

Article · Source: OpenAlex

2020

Protective effect of bergapten in acetic acid-induced colitis in rats

Emmanuel A. Adakudugu, Elvis Ofori Ameyaw, Ernest Obese, Robert Peter Biney et al.

Heliyon · Article · 59 citations · Source: OpenAlex + ORCID

Structural elucidation and in vivo anti-arthritic activity of β-amyrin and polpunonic acid isolated from the root bark of Ziziphus abyssinica HochstEx. A Rich (Rhamnaceae)

Isaac Tabiri Henneh, Boshi Huang, Faik N. Musayev, Rana Al Hashimi et al.

Bioorganic Chemistry · Article · 19 citations · Source: OpenAlex + ORCID

Bergapten modulates ovalbumin-induced asthma

Emmanuel A. Adakudugu, David D. Obiri, Elvis Ofori Ameyaw, Ernest Obese et al.

Scientific African · Article · 8 citations · Source: OpenAlex + ORCID

Sub-chronic toxicity evaluation of top three commercial herbal antimalarial preparations in the Kumasi metropolis, Ghana

Frank Adusei‐Mensah, Carina Tikkanen‐Kaukanen, Jussi Kauhanen, Isaac Tabiri Henneh et al.

Bioscience Reports · Article · 6 citations · Source: OpenAlex + ORCID

Leaf and root bark extracts of Ziziphus abyssinica Hochst ex. A. Rich (Rhamnaceae) ameliorate hepatic, renal and splenic injuries induced by phenylhydrazine in rats

Isaac Tabiri Henneh, Phyllis Elsie Owusu Agyei, Ernest Obese, Robert Peter Biney et al.

Journal of Basic and Clinical Physiology and Pharmacology · Article · 5 citations · Source: OpenAlex + ORCID

Effects of three herb-based alcoholic beverages manufactured in Ghana on sperm characteristics and reproductive hormones in rats

Robert Peter Biney, Phyllis Elsie Owusu Agyei, Elvis Ofori Ameyaw, John Kofi Afortude et al.

Scientific African · Article · 3 citations · Source: OpenAlex + ORCID

In-vitro Anti-cercarial activity of extracts and steroidal alkaloids from the stem bark of Holarrhena floribunda (G. Don) Dur. & Schinz

Isaac Kingsley Amponsah, Francis Ackah Armah, John Alake, Benjamin Kingsley Harley et al.

International Journal of Phytomedicine · Article · 2 citations · Source: OpenAlex

CCDC 1909815: Experimental Crystal Structure Determination

Isaac Tabiri Henneh, Boshi Huang, Faik N. Musayev, Rana Al Hashimi et al.

The Cambridge Structural Database · Dataset · Source: OpenAlex

2019

Anti-inflammatory, anti-nociceptive and antipyretic activity of young and old leaves of Vernonia amygdalina

Du-Bois Asante, Isaac Tabiri Henneh, Desmond Omane Acheampong, Foster Kyei et al.

Biomedicine & Pharmacotherapy · Article · 61 citations · Source: OpenAlex + ORCID

In vitro Cercaricidal Activity of Fractions and Isolated Compounds of Erythrophleum ivorense (Fabaceae) Root Bark against Schistosoma haematobium

Francis Ackah Armah, Benjamin Amoani, Isaac Tabiri Henneh, Rita A. Dickson et al.

International Journal of TROPICAL DISEASE & Health · Article · 2 citations · Source: OpenAlex + ORCID

Pharmacological evaluation of extract and isolated compounds from the root bark of Ziziphus Abyssinica Hochst ex. A rich (Rhamnaceae)

Isaac Tabiri Henneh

Dissertation · 1 citation · Source: OpenAlex

Sub-chronic toxicity evaluation of top two commercial herbal anti-malarial preparations in Kumasi area (metropolis), Ghana

Frank Adusei‐Mensah, Martins Ekor, Jussi Kauhanen, Isaac Tabiri Henneh et al.

The Journal of Alternative and Complementary Medicine · Article · Source: OpenAlex

2018

Stem Bark Extract of Sterculia setigera Delile Exhibits Anti-inflammatory Properties through Membrane Stabilization, Inhibition of Protein Denaturation and Prostaglandin E2 Activity

Isaac Tabiri Henneh, Robertson Akrofi, Elvis Ofori Ameyaw, Daniels Konja et al.

Journal of Pharmaceutical Research International · Article · 16 citations · Source: OpenAlex + ORCID

Isobolographic analysis of co-administration of two plant-derived antiplasmodial drug candidates, cryptolepine and xylopic acid, in Plasmodium berghei

Elvis Ofori Ameyaw, Kodwo B. Asmah, Robert Peter Biney, Isaac Tabiri Henneh et al.

Malaria Journal · Article · 15 citations · Source: OpenAlex + ORCID

Phytochemical Screening and Anti-Inflammatory Properties of the Hydroethanolic Leaf Extract of Calotropis procera (Ait). R. Br. (Apocynaceae)

Ernest Obese, Elvis Ofori Ameyaw, Robert Peter Biney, Isaac Tabiri Henneh et al.

Journal of Pharmaceutical Research International · Article · 15 citations · Source: OpenAlex + ORCID

2017

Hydro-ethanolic leaf extract of Ziziphus abyssinica Hochst Ex A. Rich (Rhamnaceae) exhibits anti-nociceptive effects in murine models

Eric Boakye‐Gyasi, Isaac Tabiri Henneh, Wonder Kofi Mensah Abotsi, Elvis Ofori Ameyaw et al.

BMC Complementary and Alternative Medicine · Article · 20 citations · Source: OpenAlex + ORCID

Possible mechanisms involved in the anti-nociceptive effects of hydro-ethanolic leaf extract of Ziziphus abyssinica

Eric Boakye‐Gyasi, Isaac Tabiri Henneh, Wonder Kofi Mensah Abotsi, Elvis Ofori Ameyaw et al.

Pharmaceutical Biology · Article · 13 citations · Source: OpenAlex + ORCID

Safety Concern Following Sub-acute Exposure to the Popular Food Additives, Sorghum bicolor and Saltpetre, Either Separately or in Combination in Sprague-Dawley Rats

Martins Ekor, Daniels Konja, Isaac Tabiri Henneh, Samuel Badu-Nyark et al.

Pharmacologia · Article · 1 citation · Source: OpenAlex + ORCID

2016

Pentobarbitone-induced sleeping time and sub-acute toxicity studies of Trichilia monadelpha aqueous extract

George Owusu, Meshack Antwi-Adjei, Isaac Tabiri Henneh

International Journal of Basic & Clinical Pharmacology · Article · 5 citations · Source: OpenAlex + ORCID

OpenAlex updated 10 Sep 2026

Honors & affiliations

Member
Pharmaceutical Society of Ghana (PSGh) · 2014

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